Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700157 | 0.81 | RAD52 (0.35) | RAD52ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL8984508 | 0.81 | ALDH1A1 (0.33) | ALDH1A1HPGDHSD17B10CYP1A1CYP1A2 | |
| SCHEMBL8737325 | 0.78 | OXTR (0.33) | KDM4EGAAMAPT | |
| SCHEMBL20567800 | 0.73 | ALDH1A1 (0.33) | ALDH1A1HPGDHSD17B10CYP1A1CYP1A2 | |
| SCHEMBL27533775 | 0.73 | ALDH1A1 (0.33) | ALDH1A1HPGDHSD17B10KDM4ECYP1A1 | |
| SCHEMBL28817812 | 0.73 | ALDH1A1 (0.33) | RAD52ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL27298252 | 0.73 | ALDH1A1 (0.33) | ALDH1A1HPGDHSD17B10CYP1A1CYP1A2 | |
| SCHEMBL18039128 | 0.73 | ALDH1A1 (0.30) | ALDH1A1HPGDHSD17B10CYP1A1CYP1A2 | |
| SCHEMBL11874656 | 0.73 | TYMS (0.33) | RAD52MAPTTYMS | |
| SCHEMBL28262841 | 0.72 | ALDH1A1 (0.32) | ALDH1A1HPGDHSD17B10CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642483-B1 | CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF | DOW CHEMICAL CO (US) | 1998-02-18 | — | — | EP | disclosed |
| US-5227560-A | Vinylene or exomethylene groups from active methine compounds | THE DOW CHEMICAL COMPANY (US) | 1993-07-13 | — | — | US | disclosed |