Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.31 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700157 | 0.90 | RAD52 (0.35) | TYMSMEN1MAPTMAPK1KMT2A | |
| SCHEMBL28209755 | 0.74 | NPSR1 (0.32) | — | |
| SCHEMBL8736618 | 0.73 | RAD52 (0.33) | TYMSMAPTRAD52 | |
| SCHEMBL626688 | 0.72 | TXNRD1 (0.31) | TXNRD1TXNRD3TXNRD2MEN1MAPT | |
| SCHEMBL28050408 | 0.71 | TXNRD1 (0.31) | TXNRD1TXNRD3TXNRD2MEN1MAPT | |
| SCHEMBL1666657 | 0.69 | KDM4E (0.34) | TYMSTXNRD1TXNRD3TXNRD2MEN1 | |
| SCHEMBL28939001 | 0.69 | UGT2B7 (0.34) | — | |
| SCHEMBL29387054 | 0.68 | KDM4E (0.39) | MAPT | |
| SCHEMBL251287 | 0.68 | KDM4E (0.39) | MAPT | |
| SCHEMBL20567800 | 0.68 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933690-A | Dihalobutenediol containing urethane foam compositions | ICI UNITED STATES INC. (US) | 1976-01-20 | — | — | US | disclosed |