Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27317852 | 0.90 | LMNA (0.57) | LMNAGAAJAK2MAPTHTR7 | |
| SCHEMBL9152183 | 0.84 | GAA (0.72) | LMNAGAAJAK2MAPTTP53 | |
| SCHEMBL904496 | 0.83 | LMNA (0.53) | LMNAGAAJAK2MAPTPDE5A | |
| Methane SCHEMBL7356487 | 0.82 | GAA (0.69) | LMNAGAAJAK2MAPTTP53 | |
| SCHEMBL6675757 | 0.81 | LMNA (0.52) | LMNAGAAJAK2MAPTPDE5A | |
| SCHEMBL9123355 | 0.81 | LMNA (0.53) | LMNAGAAJAK2MAPTPDE5A | |
| SCHEMBL9257284 | 0.81 | LMNA (0.53) | LMNAGAAJAK2MAPTPDE5A | |
| SCHEMBL27980667 | 0.81 | LMNA (0.53) | LMNAGAAJAK2MAPTPDE5A | |
| SCHEMBL27555571 | 0.80 | GAA (0.55) | LMNAGAAJAK2MAPTHTR7 | |
| Alcohol SCHEMBL1545296 | 0.79 | GAA (0.64) | LMNAGAAJAK2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641805-B1 | Antimicrobial polymers and compositions containing them | RECKITT & COLMAN INC (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5532290-A | SANITIZING COMPOSITION | RECKITT & COLMAN INC. (US) | 1996-07-02 | — | — | US | disclosed |
| EP-0641805-A1 | Antimicrobial polymers and compositions containing them | Reckitt & Colman Inc. (US) | 1995-03-08 | — | — | EP | disclosed |