Pentane

Pentane

SCHEMBL8736679

CCCCC.CCCCC.CCCCC(C(Cl)Cl)C(Cl)Cl

nearest known ligand 0.41

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.41
LMNA P02545 1/20 0.41
DNM1 Q05193 2/20 0.39
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
CA2 P00918 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
CYP3A4 P08684 1/20 0.33
FDPS P14324 1/20 0.33
MAPK1 P28482 1/20 0.32
OPRM1 P35372 1/20 0.32
SLC22A1 O15245 2/20 0.32
SLC22A2 O15244 1/20 0.32
THRB P10828 1/20 0.32
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL580067 0.88 OPRM1 (0.43) TSHRLMNADNM1ALDH1A1FDPS
Hexane SCHEMBL244151 0.88 OPRM1 (0.43) TSHRLMNADNM1ALDH1A1FDPS
Hexane SCHEMBL1080155 0.88 OPRM1 (0.43) TSHRLMNADNM1ALDH1A1FDPS
SCHEMBL1081317 0.88 OPRM1 (0.43) TSHRLMNADNM1ALDH1A1FDPS
Heptane SCHEMBL1323676 0.86 TSHR (0.44) TSHRLMNADNM1ALDH1A1FDPS
Pentane SCHEMBL1914435 0.81 LMNA (0.30) TSHRLMNA
SCHEMBL11395349 0.78 TSHR (0.32) TSHRTDP1
Pentane SCHEMBL9002883 0.73
Pentane SCHEMBL968651 0.73
SCHEMBL25428162 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0824096-A2 Process for the preparation of halogenated (meth)acrylic esters and poly (meth) arcylates obtained with said (meth)acrylic esters Akzo Nobel N.V. (NL) 1998-02-18 EP disclosed