SCHEMBL8736704

SCHEMBL8736704

CCC(OC(=O)C=CC(=O)OC1CCCCC1)[Si]1(C)CCC(C)(C)O[Si]1(C)C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8736053 0.88
SCHEMBL8736146 0.86
SCHEMBL9239075 0.83 KEAP1 (0.32)
SCHEMBL7178450 0.83 HCAR2 (0.36)
SCHEMBL9243501 0.82 HCAR2 (0.35)
SCHEMBL8734555 0.81
SCHEMBL9576515 0.81 PRKCA (0.31)
SCHEMBL9283994 0.81
SCHEMBL9244994 0.74
SCHEMBL8736690 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722959-B1 Highly oxygen-permeable heat-resistant material MENICON CO LTD (JP) 1998-04-08 EP disclosed
EP-0722959-A2 Highly oxygen-permeable heat-resistant material Menicon Co., Ltd. (JP) 1996-07-24 EP disclosed
EP-0434362-B1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution TOMEI SANGYO KK (JP) 1995-03-22 EP disclosed
EP-0433046-B1 Polymer-type polymerization initiator TOMEI SANGYO KK (JP) 1994-08-10 EP disclosed
EP-0219884-B1 HARD CONTACT LENS MATERIAL Tomei Sangyo Kabushiki Kaisha (JP) 1993-09-29 EP disclosed
US-5142009-A Crosslinked blend of fumaric acid diesters TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-08-25 US disclosed
US-5134213-A N-Vinyllactam-Monoperoxyfumarate Terpolymer TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-07-28 US disclosed
US-5082912-A For graft polymerization, surfactants TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-01-21 US disclosed
EP-0434362-A1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-26 EP disclosed
EP-0433046-A2 Polymer-type polymerization initiator Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-19 EP disclosed
US-4868260-A OXYGEN PERMEABILITY TOMEI SANGYO KABUSHIKI KAISHA (JP) 1989-09-19 US disclosed
EP-0219884-A2 Hard contact lens material Tomei Sangyo Kabushiki Kaisha (JP) 1987-04-29 EP disclosed