Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGFBP3 | P17936 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8735609 | 0.98 | IGFBP3 (0.37) | IGFBP3CA2MEN1KMT2AKCNQ3 | |
| SCHEMBL8737430 | 0.90 | GAA (0.50) | IGFBP3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL20219469 | 0.90 | IGFBP3 (0.40) | IGFBP3CA2MEN1KMT2AKCNQ3 | |
| SCHEMBL12086587 | 0.90 | IGFBP3 (0.40) | IGFBP3CA2MEN1KMT2AKCNQ3 | |
| SCHEMBL13088088 | 0.89 | IGFBP3 (0.42) | IGFBP3MEN1KMT2AKCNQ3KCNQ2 | |
| SCHEMBL8735605 | 0.86 | GAA (0.52) | IGFBP3KCNQ3KCNQ2MAPTALDH1A1 | |
| SCHEMBL8736859 | 0.85 | IGFBP3 (0.42) | IGFBP3MEN1KMT2AKCNQ3KCNQ2 | |
| SCHEMBL8734242 | 0.84 | GAA (0.55) | IGFBP3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8736812 | 0.84 | KCNQ3 (0.45) | IGFBP3KCNQ3KCNQ2MAPTALDH1A1 | |
| SCHEMBL8735142 | 0.83 | RAB9A (0.43) | IGFBP3MEN1KMT2AKCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120130117-A1 | AROMATIC SULFONIUM SALT COMPOUND | ADEKA CORPORATION (JP) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130117-A1 | AROMATIC SULFONIUM SALT COMPOUND | SLC6A19, ARSA, PAH | IGFBP3 4792/4885CA2 413/4885MEN1 3308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.