SCHEMBL8737324

SCHEMBL8737324

Oc1nc(F)c(F)c(Cl)c1F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7028015 0.80 MEN1 (0.36)
SCHEMBL8735023 0.79 CES2 (0.31) CES2CES1
SCHEMBL8735394 0.79 CES2 (0.31) CES2CES1
SCHEMBL31290292 0.75
SCHEMBL8465838 0.74 MEN1 (0.31)
SCHEMBL8735002 0.74 CES2 (0.31) CES2CES1
SCHEMBL10744284 0.69 MEN1 (0.37)
SCHEMBL23258946 0.68
SCHEMBL8735431 0.68 MEN1 (0.34)
SCHEMBL20502810 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0824096-A2 Process for the preparation of halogenated (meth)acrylic esters and poly (meth) arcylates obtained with said (meth)acrylic esters Akzo Nobel N.V. (NL) 1998-02-18 EP disclosed