SCHEMBL8465838

SCHEMBL8465838

Fc1nc(F)c(F)c(Cl)c1F.Fc1nc(F)c(F)c(S)c1F

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7022108 0.86 MEN1 (0.36) MEN1KMT2AMAPTHTT
SCHEMBL7028015 0.86 MEN1 (0.36) MEN1KMT2AGAAMAPTHTT
SCHEMBL10744284 0.75 MEN1 (0.37) MEN1KMT2AGAAMAPTHTT
SCHEMBL8737324 0.74 CES2 (0.31)
SCHEMBL49490 0.74
SCHEMBL502245 0.69 MEN1 (0.37) MEN1KMT2AGAAMAPTHTT
SCHEMBL23258946 0.68
SCHEMBL17156504 0.68 MEN1 (0.34) MEN1KMT2AGAA
SCHEMBL20502810 0.68
SCHEMBL282140 0.67 MEN1 (0.35) MEN1KMT2AGAAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5912243-A NOVEL COMPOUNDS FOR CONTROLLING NEMATODES, INSECT OR ACARID PESTS ZENECA LIMITED (GB) 1999-06-15 US disclosed