Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733951 | 0.96 | THRB (0.36) | THRBEGFR | |
| SCHEMBL8733946 | 0.94 | THRB (0.35) | THRBEGFR | |
| SCHEMBL8736687 | 0.91 | CES2 (0.32) | THRBEGFRCES2CES1 | |
| SCHEMBL8734960 | 0.89 | CES2 (0.31) | THRBEGFRCES2CES1 | |
| SCHEMBL8737346 | 0.89 | THRB (0.31) | THRBEGFR | |
| SCHEMBL8735405 | 0.89 | CES2 (0.33) | THRBEGFRCES2CES1 | |
| SCHEMBL225748 | 0.88 | THRB (0.40) | THRB | |
| SCHEMBL2579041 | 0.86 | THRB (0.41) | THRB | |
| SCHEMBL6433548 | 0.85 | THRB (0.33) | THRBEGFR | |
| SCHEMBL6433544 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824096-A2 | Process for the preparation of halogenated (meth)acrylic esters and poly (meth) arcylates obtained with said (meth)acrylic esters | Akzo Nobel N.V. (NL) | 1998-02-18 | — | — | EP | disclosed |