SCHEMBL2579041

SCHEMBL2579041

C=CC(=O)Oc1c(F)c(F)c(OC(=O)C=C)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.41
TSHR P16473 6/20 0.37
HPGD P15428 1/20 0.35
ALDH1A1 P00352 5/20 0.35
TP53 P04637 3/20 0.34
HIF1A Q16665 3/20 0.34
CYP3A4 P08684 2/20 0.34
HSD17B10 Q99714 1/20 0.34
THRA P10827 1/20 0.34
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL225748 0.98 THRB (0.40) THRBTSHRHPGDALDH1A1TP53
SCHEMBL1098070 0.93 THRB (0.38) THRBTSHRHPGDALDH1A1TP53
SCHEMBL8733951 0.89 THRB (0.36) THRBTSHRHPGDTHRA
Acrylamide SCHEMBL28026684 0.89 TSHR (0.44) THRBTSHRHPGDALDH1A1HSD17B10
SCHEMBL6433342 0.89 THRB (0.36) THRBTSHRHPGDTHRA
SCHEMBL9614267 0.88 THRB (0.35) THRBTSHRHPGDSMN1; SMN2
SCHEMBL8733946 0.88 THRB (0.35) THRBTSHR
SCHEMBL26688609 0.88 THRB (0.35) THRBTSHR
SCHEMBL26363017 0.88 THRB (0.35) THRBTSHR
SCHEMBL8737374 0.86 THRB (0.34) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022118745-A1 LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2022-06-09 WO disclosed
WO-2022102624-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF 日産化学株式会社 2022-05-19 WO disclosed
CN-106462011-B Liquid crystal display element, liquid crystal alignment film, and liquid crystal alignment treatment agent 日产化学工业株式会社 2021-11-12 CN disclosed
EP-3159737-B1 LIQUID CRYSTAL DISPLAY ELEMENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL ALIGNMENT TREATMENT AGENT NISSAN CHEMICAL CORP (JP) 2021-05-26 EP disclosed
CN-107077024-B Liquid crystal display element 日产化学工业株式会社 2020-11-17 CN disclosed
CN-107003570-B Liquid crystal display element 日产化学工业株式会社 2020-10-09 CN disclosed
CN-107003571-B Liquid crystal display element 日产化学工业株式会社 2020-10-09 CN disclosed
US-10647816-B2 Liquid crystal display device NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-05-12 US disclosed
US-10386681-B2 Liquid crystal display element NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-08-20 US disclosed
EP-3200022-B1 LIQUID CRYSTAL DISPLAY DEVICE NISSAN CHEMICAL CORP (JP) 2019-06-26 EP disclosed
US-20020080320-A1 Liquid crystal display device PIXEL DISPLAY LLC 2002-06-27 US disclosed
US-20020024627-A1 Liquid crystal display device and method of manufacturing the same NEC CORPORATION (JP) 2002-02-28 US disclosed
US-20010026344-A1 Liquid crystal display device and method of manufacturing the same NEC CORPORATION (JP) 2001-10-04 US disclosed
US-6256082-B1 Liquid crystal display with a liquid crystal orientation controlling electrode and processes for manufacturing and driving thereof NEC CORPORATION (JP) 2001-07-03 US disclosed
US-6177976-B1 Liquid crystal display NEC CORPORATION (JP) 2001-01-23 US disclosed
US-6160604-A Liquid crystal display with pixel electrode having aperture containing additional electrode NEC CORPORATION (JP) 2000-12-12 US disclosed
US-6115093-A Liquid crystal display device having at least two micro areas of liquid crystal layer capable of being built up from a center of each pixel NEC CORPORATION (JP) 2000-09-05 US disclosed
US-5963290-A Liquid crystal display NEC CORPORATION (JP) 1999-10-05 US disclosed
US-5959707-A Liquid crystal display having domains with different tilted-up directions as well as domains with different twist directions of lc molecules NEC CORPORATION (JP) 1999-09-28 US disclosed
EP-0805373-A2 Liquid crystal display NEC CORPORATION (JP) 1997-11-05 EP disclosed