Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAK | O14976 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734231 | 0.90 | ABCB1 (0.41) | LMNAABCB1MEN1KMT2AMAPK1 | |
| SCHEMBL8735151 | 0.81 | IGFBP3 (0.39) | LMNAPOLBMAPTKCNQ3KCNQ2 | |
| SCHEMBL8734242 | 0.79 | GAA (0.55) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL8735605 | 0.79 | GAA (0.52) | LMNAMAPTKCNQ3KCNQ2MAPK1 | |
| SCHEMBL8736808 | 0.76 | GAA (0.48) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL8737430 | 0.75 | GAA (0.50) | LMNAMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL8736811 | 0.74 | ELANE (0.41) | LMNAPOLBMAPTNPSR1KCNQ3 | |
| SCHEMBL8734233 | 0.74 | ALDH1A1 (0.41) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL13088088 | 0.73 | IGFBP3 (0.42) | POLBMAPTKCNQ3KCNQ2MEN1 | |
| SCHEMBL8736856 | 0.73 | IGFBP3 (0.41) | MAPTKCNQ3KCNQ2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120130117-A1 | AROMATIC SULFONIUM SALT COMPOUND | ADEKA CORPORATION (JP) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130117-A1 | AROMATIC SULFONIUM SALT COMPOUND | SLC6A19, ARSA, PAH | LMNA 4190/4885POLB 1342/4885MAPT 2842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.