Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.77 |
| ▸ | DRD4 | P21917 | 13/20 | 0.77 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.74 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8738579 | 1.00 | DRD2 (0.77) | DRD2DRD4SLC2A1MCHR1HTR2A | |
| SCHEMBL7218171 | 0.93 | TMEM97 (0.74) | DRD2DRD4MCHR1 | |
| SCHEMBL7694199 | 0.89 | DRD2 (0.85) | DRD2DRD4MCHR1HTR2A | |
| SCHEMBL7694198 | 0.89 | DRD2 (0.85) | DRD2DRD4MCHR1HTR2A | |
| SCHEMBL11555632 | 0.87 | DRD2 (0.82) | DRD2DRD4MCHR1HTR2A | |
| SCHEMBL8706290 | 0.87 | DRD2 (1.00) | DRD2DRD4MCHR1HTR2A | |
| SCHEMBL8707354 | 0.87 | DRD2 (1.00) | DRD2DRD4MCHR1HTR2A | |
| SCHEMBL2900269 | 0.86 | TMEM97 (0.86) | DRD2DRD4MCHR1HTR2A | |
| SCHEMBL8236258 | 0.86 | TMEM97 (0.86) | DRD2DRD4MCHR1HTR2A | |
| SCHEMBL8706273 | 0.84 | DRD2 (0.89) | DRD2DRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068589-A2 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS (US) | 2012-05-24 | — | — | WO | disclosed |