Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8739618 | 0.96 | PAOX (0.38) | PAOXKMT2AHRH3THRATHRB | |
| SCHEMBL19829897 | 0.95 | PAOX (0.37) | PAOXKMT2ATHRATHRB | |
| SCHEMBL8738807 | 0.94 | PAOX (0.38) | PAOXKMT2ATHRATHRB | |
| SCHEMBL25820446 | 0.94 | PAOX (0.38) | PAOXKMT2ATHRATHRB | |
| SCHEMBL10099918 | 0.92 | PAOX (0.35) | PAOXKMT2ATHRATHRB | |
| SCHEMBL25820457 | 0.91 | PAOX (0.39) | PAOXKMT2AHRH3THRATHRB | |
| SCHEMBL8739109 | 0.90 | THRA (0.40) | PAOXTHRATHRB | |
| SCHEMBL26872388 | 0.90 | ACHE (0.36) | PAOXKMT2AHRH3THRATHRB | |
| SCHEMBL23762158 | 0.87 | PAOX (0.35) | PAOXKMT2A | |
| SCHEMBL17126966 | 0.87 | PAOX (0.34) | PAOXKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8992991-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-03-31 | — | — | US | disclosed |
| US-20120128782-A1 | Multicomponent Degradable Cationic Polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120128782-A1 | Multicomponent Degradable Cationic Polymers | PEF1, FIBP, PARN | PAOX 1525/4885KMT2A 2543/4885HRH3 2244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.