Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25820446 | 0.99 | PAOX (0.38) | PAOXACHETHRATHRBRAB9A | |
| SCHEMBL8738807 | 0.99 | PAOX (0.38) | PAOXACHETHRATHRBRAB9A | |
| SCHEMBL8739618 | 0.99 | PAOX (0.38) | PAOXACHETHRATHRBRAB9A | |
| SCHEMBL25820457 | 0.96 | PAOX (0.39) | PAOXACHETHRATHRBRAB9A | |
| SCHEMBL8739109 | 0.95 | THRA (0.40) | PAOXACHETHRATHRB | |
| SCHEMBL8738445 | 0.95 | PAOX (0.38) | PAOXTHRATHRBKMT2A | |
| SCHEMBL10099918 | 0.95 | PAOX (0.35) | PAOXACHETHRATHRBKMT2A | |
| SCHEMBL26872388 | 0.95 | ACHE (0.36) | PAOXACHETHRATHRBKMT2A | |
| SCHEMBL8739614 | 0.90 | PAOX (0.37) | PAOXACHE | |
| SCHEMBL23762158 | 0.90 | PAOX (0.35) | PAOXKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180028455-A1 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180028455-A1 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | VEGFA, IAPP, FLT1 | PAOX 3116/4885ACHE 4729/4885THRA 4074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.