SCHEMBL8738592

SCHEMBL8738592

CCON1C(=O)N(OCC)C2C1N(OCC)C(=O)N2OCC

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
F2 P00734 1/20 0.33
ELANE P08246 1/20 0.33
CTSG P08311 1/20 0.33
CTRC Q99895 1/20 0.33
TP53 P04637 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18102232 0.80 L3MBTL1 (0.33) L3MBTL1
SCHEMBL17790263 0.74 L3MBTL1 (0.36) L3MBTL1
SCHEMBL15362355 0.69 ADRA2C (0.45) ADRA2CTP53GAAKMT2A
SCHEMBL27646212 0.64 CHRM2 (0.37) KMT2A
SCHEMBL17888801 0.63 ADRA2C (0.33) ADRA2C
SCHEMBL27982229 0.63 F2 (0.33) F2ELANECTSGCTRC
SCHEMBL19451104 0.63 KMT2A (0.36) KMT2A
SCHEMBL248989 0.60
SCHEMBL11696795 0.59
SCHEMBL1710103 0.58 ALOX12 (0.41) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8946026-B2 Methods of fabricating a semiconductor device including metal gate electrodes SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-02-03 US disclosed
US-20120129331-A1 METHODS OF FABRICATING A SEMICONDUCTOR DEVICE INCLUDING METAL GATE ELECTRODES SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-05-24 US disclosed