SCHEMBL873904

SCHEMBL873904

CC(C=O)c1ncc[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6158339 0.79
SCHEMBL10645911 0.79
SCHEMBL3322472 0.78 ALDH1A1 (0.36)
SCHEMBL839758 0.76
SCHEMBL16192126 0.75
SCHEMBL28913437 0.75
SCHEMBL29046781 0.75 ADRA2A (0.53)
SCHEMBL189942 0.75
SCHEMBL8305509 0.75 FPR2 (0.44)
SCHEMBL10696546 0.75 FPR2 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2643000-A2 THERAPEUTIC PIPERAZINES Dart Neuroscience (Cayman) Ltd (KY) 2013-10-02 EP claimed
WO-2012040258-A2 THERAPEUTIC PIPERAZINES HELICON THERAPEUTICS, INC. (US) 2012-03-29 WO claimed
US-20110065691-A1 THERAPEUTIC PIPERAZINES DART NEUROSCIENCE (CAYMAN) LTD. (KY) 2011-03-17 US claimed
US-9624200-B2 Therapeutic piperazines DART NEUROSCIENCE (CAYMAN) LTD. (KY) 2017-04-18 US disclosed
US-20150087645-A1 THERAPEUTIC PIPERAZINES HELICON THERAPEUTICS, INC. 2015-03-26 US disclosed
US-8927546-B2 Therapeutic piperazines DART NEUROSCIENCE (CAYMAN) LTD. (KY) 2015-01-06 US disclosed
EP-2643000-A2 THERAPEUTIC PIPERAZINES Dart Neuroscience (Cayman) Ltd (KY) 2013-10-02 EP disclosed
WO-2012040258-A2 THERAPEUTIC PIPERAZINES HELICON THERAPEUTICS, INC. (US) 2012-03-29 WO disclosed
US-20110065691-A1 THERAPEUTIC PIPERAZINES DART NEUROSCIENCE (CAYMAN) LTD. (KY) 2011-03-17 US disclosed
WO-2009141738-A2 MODIFIED DRUGS FOR USE IN LIPOSOMAL NANOPARTICLES THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2009-11-26 WO disclosed
CN-101001852-A Pyrazole derivatives DAIICHI SEIYAKU CO (JP) 2007-07-18 CN disclosed
US-7054140-B2 Electrolytic capacitor and electrode foil used for electrolytic capacitor NIPPON CHEMI-CON CORP. (JP) 2006-05-30 US disclosed
US-20040212950-A1 Electrolytic capacitor and electrode foil used for electrolytic capacitor NIPPON CHEMI-CON CORPORATION (JP) 2004-10-28 US disclosed
EP-1398806-A1 ELECTROLYTIC CAPACITOR AND ELECTROLYTIC CAPACITOR&amp;minus;USE ELECTRODE FOIL USED THEREFOR Nippon Chemi-Con Corporation (JP) 2004-03-17 EP disclosed
EP-0217372-A2 Polyoxygenated labdane derivatives, process for their preparation and their use as medicaments HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-08 EP disclosed
US-4396530-A Mineral acid demulsification of surfactant-containing emulsion MARATHON OIL COMPANY (US) 1983-08-02 US disclosed