Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 16/20 | 1.00 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8738979 | 0.92 | EZH2 (0.85) | EZH2 | |
| SCHEMBL8739720 | 0.90 | EZH2 (0.82) | EZH2 | |
| SCHEMBL8738645 | 0.90 | EZH2 (0.81) | EZH2 | |
| SCHEMBL8738695 | 0.89 | EZH2 (0.91) | EZH2SLC2A1GAA | |
| SCHEMBL8739015 | 0.86 | EZH2 (0.77) | EZH2SLC2A1 | |
| SCHEMBL8738647 | 0.86 | EZH2 (0.75) | EZH2GAA | |
| SCHEMBL8739474 | 0.85 | EZH2 (0.75) | EZH2 | |
| SCHEMBL8738997 | 0.85 | EZH2 (1.00) | EZH2SLC2A1 | |
| SCHEMBL8738144 | 0.85 | EZH2 (1.00) | EZH2 | |
| SCHEMBL8738171 | 0.84 | EZH2 (0.74) | EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068589-A2 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS (US) | 2012-05-24 | — | — | WO | disclosed |