Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.78 |
| ▸ | GAA | P10253 | 5/20 | 0.78 |
| ▸ | MAPT | P10636 | 5/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | PDE5A | O76074 | 1/20 | 0.64 |
| ▸ | PDE1A | P54750 | 1/20 | 0.64 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.64 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8739499 | 0.92 | MEN1 (0.82) | MEN1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL6114308 | 0.87 | MEN1 (0.78) | MEN1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL14058795 | 0.87 | MEN1 (0.78) | MEN1KMT2AGAAMAPTMAPK1 | |
| Bromide SCHEMBL14053360 | 0.86 | MEN1 (0.77) | MEN1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL6113962 | 0.85 | MMP9 (0.75) | MEN1KMT2AGAAMAPTNPSR1 | |
| SCHEMBL8737941 | 0.84 | MEN1 (0.71) | MEN1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL8737705 | 0.84 | MEN1 (0.71) | MEN1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL6114270 | 0.84 | MEN1 (0.74) | MEN1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL8738372 | 0.84 | MEN1 (0.74) | MEN1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL14053325 | 0.84 | OPRM1 (0.83) | MEN1KMT2AGAAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068209-A2 | BISTHIAZOLE INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION | JANSSEN PHARMACEUTICA NV (BE) | 2012-05-24 | — | — | WO | disclosed |