Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | LIPE | Q05469 | 14/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581981 | 0.87 | LMNA (0.63) | LMNARAB9ALIPEBCHE | |
| SCHEMBL27396537 | 0.80 | LMNA (0.60) | LMNARAB9ALIPEBCHE | |
| SCHEMBL11351938 | 0.79 | MAPT (0.69) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL8909901 | 0.79 | LMNA (0.66) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL9255996 | 0.78 | MAPK1 (0.74) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL9304488 | 0.78 | LMNA (0.58) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL4317357 | 0.78 | LMNA (0.75) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL9108246 | 0.77 | LMNA (0.63) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL9267594 | 0.77 | LMNA (0.63) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL10944778 | 0.76 | LMNA (0.62) | LMNARAB9ALIPEMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5675017-A | REACTING VINY ETHER DERIVATIVE WITH HYDRZINE OR SUBSTITUTED HYDRAZINE TO FORM A CHEMICAL INTERMEDIATE, REACTING INTERMEDIATE WITH SUBSTITUTED HALIDE OR DIALKYL SULFATE | MONSANTO COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| US-5672715-A | Herbicidal substituted 3-aryl-pyrazoles | MONSANTO COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| EP-0439857-B1 | A solvent-free process for the preparation of ((pyridinyloxy)phenoxy) propionate derivatives | DOWELANCO (US) | 1994-12-21 | — | — | EP | disclosed |
| EP-0040478-A1 | Process for preparing pyridine derivatives and intermediates useful in the process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-11-25 | — | — | EP | disclosed |