Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805779 | 0.80 | KDM4E (0.46) | DNM1ALOX15SUCNR1HPGDKMT2A | |
| SCHEMBL9805775 | 0.80 | KDM4E (0.46) | DNM1ALOX15SUCNR1HPGDKMT2A | |
| SCHEMBL8740351 | 0.77 | KMT2A (0.44) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL11246906 | 0.73 | TSHR (0.39) | ALDH1A1SMN1; SMN2DNM1SUCNR1KMT2A | |
| SCHEMBL445252 | 0.70 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2GAADNM1POLB | |
| SCHEMBL8740372 | 0.69 | NPSR1 (0.47) | ALDH1A1POLBKMT2A | |
| SCHEMBL11151811 | 0.68 | KDM4E (0.43) | MAPTDNM1ALOX15SUCNR1HPGD | |
| SCHEMBL11234189 | 0.68 | KDM4E (0.43) | SMN1; SMN2GAADNM1POLBKMT2A | |
| SCHEMBL22043405 | 0.67 | MAPT (0.55) | ALDH1A1SMN1; SMN2GAAMAPTALOX15 | |
| SCHEMBL1922659 | 0.67 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2DNM1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669002-A4 | N-TERMINAL SEQUENCING OF PROTEINS AND PEPTIDES. | HOPE CITY (US) | 1997-12-10 | — | — | EP | disclosed |
| EP-0669002-A1 | N-TERMINAL SEQUENCING OF PROTEINS AND PEPTIDES | CITY OF HOPE (US) | 1995-08-30 | — | — | EP | disclosed |
| US-5432091-A | N-terminal sequencing of proteins and peptides | CITY OF HOPE (US) | 1995-07-11 | — | — | US | disclosed |
| WO-1995008119-A1 | N-TERMINAL SEQUENCING OF PROTEINS AND PEPTIDES | CITY OF HOPE (US) | 1995-03-23 | — | — | WO | disclosed |