Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.31 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.30 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | GGT1 | P19440 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805775 | 0.90 | KDM4E (0.46) | TSHRKDM4ENPC1MEN1KMT2A | |
| SCHEMBL9805779 | 0.90 | KDM4E (0.46) | TSHRKDM4ENPC1MEN1KMT2A | |
| SCHEMBL11148996 | 0.78 | HTT (0.47) | TSHRKDM4ENPC1MAPK1ALDH1A1 | |
| SCHEMBL4910708 | 0.77 | KDM4E (0.47) | KDM4ENPC1PRMT3CARM1PRMT6 | |
| SCHEMBL11151811 | 0.76 | KDM4E (0.43) | TSHRKDM4ENPC1MAPK1SUCNR1 | |
| SCHEMBL11234189 | 0.76 | KDM4E (0.43) | TSHRKDM4ENPC1KMT2ADNM1 | |
| SCHEMBL7213859 | 0.76 | GRN (0.36) | TSHRMEN1KMT2ATGFBR1MAPK1 | |
| SCHEMBL12391612 | 0.75 | MME (0.34) | TSHRTGFBR1MAPK1 | |
| SCHEMBL27889526 | 0.74 | TGFBR1 (0.36) | TSHRKDM4ETGFBR1GGT1 | |
| SCHEMBL6947280 | 0.74 | KDM4E (0.48) | TSHRKDM4ENPC1SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326069-A | CURING AGENTS FOR POLYEPOXIDES | CIBA-GEIGY CORPORATION (US) | 1982-04-20 | — | — | US | disclosed |