SCHEMBL8740756

SCHEMBL8740756

CCOC([C]=O)CCC[C]=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL243363 0.80
SCHEMBL745667 0.78 LMNA (0.35) THRB
SCHEMBL11219104 0.78 ZDHHC7 (0.41)
SCHEMBL11614269 0.78 ZDHHC7 (0.41)
SCHEMBL3393450 0.76
SCHEMBL10382326 0.75 DNM1 (0.33)
SCHEMBL7337430 0.75
SCHEMBL5444401 0.74
SCHEMBL5965378 0.72
SCHEMBL7377390 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0771211-A4 COMPOSITIONS AND METHODS FOR THE DELIVERY OF DRUGS BY PLATELETS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES NEW ENGLAND DEACONESS HOSPITAL (US) 1997-11-12 EP disclosed
EP-0771211-A1 COMPOSITIONS AND METHODS FOR THE DELIVERY OF DRUGS BY PLATELETS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES NEW ENGLAND DEACONESS HOSPITAL CORPORATION (US) 1997-05-07 EP disclosed
WO-1996004004-A1 COMPOSITIONS AND METHODS FOR THE DELIVERY OF DRUGS BY PLATELETS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES NEW ENGLAND DEACONESS HOSPITAL CORPORATION (US) 1996-02-15 WO disclosed