Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 3/20 | 0.51 |
| ▸ | MMP2 | P08253 | 3/20 | 0.51 |
| ▸ | MMP9 | P14780 | 3/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1557405 | 1.00 | NOS2 (0.58) | NOS2PPARGTDP1HDAC2HDAC3 | |
| SCHEMBL1557402 | 1.00 | NOS2 (0.58) | NOS2PPARGTDP1HDAC2HDAC3 | |
| SCHEMBL29269198 | 0.88 | NOS2 (0.55) | NOS2PPARGTDP1HDAC2HDAC3 | |
| SCHEMBL29269199 | 0.88 | NOS2 (0.55) | NOS2PPARGTDP1HDAC2HDAC3 | |
| SCHEMBL4924078 | 0.88 | HDAC2 (0.57) | NOS2PPARGTDP1HDAC2HDAC3 | |
| SCHEMBL30448356 | 0.88 | AKR1B10 (0.53) | NOS2PPARGHDAC2HDAC3HDAC4 | |
| SCHEMBL4924084 | 0.88 | HDAC2 (0.57) | NOS2PPARGTDP1HDAC2HDAC3 | |
| SCHEMBL1558240 | 0.88 | AKR1B10 (0.53) | NOS2PPARGHDAC2HDAC3HDAC4 | |
| SCHEMBL22994397 | 0.86 | NOS2 (0.56) | NOS2PPARGTDP1HDAC2HDAC3 | |
| SCHEMBL6689458 | 0.86 | NOS2 (0.56) | NOS2PPARGTDP1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1098278-C | Cinnamic acid derivative | SEIKAGAKU KOGYO CO LTD (JP) | 2003-01-08 | — | — | CN | disclosed |
| CN-1090637-C | Crosslinked cinnamic acid hyaluronic acid derivatives and process for producing the same | SEIKAGAKU KOGYO CO LTD (JP) | 2002-09-11 | — | — | CN | disclosed |
| CN-1245812-A | Cinnamic acid derivative | SEIKAGAKU KOGYO CO LTD (JP) | 2000-03-01 | — | — | CN | disclosed |
| EP-0785768-A4 | — | — | 1997-07-30 | — | — | EP | disclosed |
| EP-0785768-A1 | O-ACYL SERINES AS DEODORANTS | THE GILLETTE COMPANY (US) | 1997-07-30 | — | — | EP | disclosed |
| CN-1133834-A | cinnamic acid derivatives | SEIKAGAKU KOGYO CO LTD (JP) | 1996-10-23 | — | — | CN | disclosed |
| WO-1995007069-A1 | O-ACYL SERINES AS DEODORANTS | THE GILLETTE COMPANY (US) | 1995-03-16 | — | — | WO | disclosed |