SCHEMBL8740875

SCHEMBL8740875

O=C(O)c1ccccc1CC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 12/20 0.49
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
FOLH1 Q04609 1/20 0.45
KDM5A P29375 1/20 0.44
KDM5B Q9UGL1 1/20 0.44
HSD11B1 P28845 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4936872 0.86 ALDH1A1 (0.47) P2RX7MEN1KMT2A
SCHEMBL27759391 0.83 RARB (0.46) P2RX7KDM4EMEN1KMT2AKDM5A
SCHEMBL27780759 0.82 KDM4E (0.47) P2RX7KDM4EMEN1KMT2AKDM5A
Phthalic Acid SCHEMBL28793332 0.76 ALDH1A1 (0.70) P2RX7KDM4E
SCHEMBL14510877 0.76 MEN1 (0.62) P2RX7KDM4EMEN1KMT2A
SCHEMBL27255420 0.74 ALDH1A1 (0.50) P2RX7KDM4EMEN1KMT2A
SCHEMBL8381564 0.74 P2RX7 (0.72) P2RX7
SCHEMBL11446784 0.73 P2RX7 (0.44) P2RX7MEN1KMT2A
SCHEMBL3175880 0.73 P2RX7 (0.48) P2RX7MEN1KMT2A
SCHEMBL5475249 0.71 KDM4E (0.53) P2RX7KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5633111-A Photoresist composition and article containing 1,2-quinonediazide and an organic phosphorous acid compound FUJI PHOTO FILM CO., LTD. (JP) 1997-05-27 US disclosed
EP-0540032-B1 Photoresist composition and etching method FUJI PHOTO FILM CO LTD (JP) 1996-03-06 EP disclosed
EP-0540032-A1 Photoresist composition and etching method FUJI PHOTO FILM CO., LTD. (JP) 1993-05-05 EP disclosed