SCHEMBL5475249

SCHEMBL5475249

O=C(O)c1ccccc1C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.53
HIF1A Q16665 1/20 0.46
EPAS1 Q99814 1/20 0.46
P2RX7 Q99572 3/20 0.45
ALDH1A1 P00352 3/20 0.45
ALOX15 P16050 2/20 0.45
MAPT P10636 2/20 0.44
HPGD P15428 2/20 0.44
ALOX12 P18054 2/20 0.44
HSD17B10 Q99714 2/20 0.44
TSHR P16473 1/20 0.44
HTT P42858 1/20 0.44
ATM Q13315 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
FAAH O00519 1/20 0.44
RARA P10276 2/20 0.43
RARB P10826 2/20 0.43
RARG P13631 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2747082 0.90 KDM4E (0.47) KDM4EHIF1AEPAS1P2RX7ALDH1A1
SCHEMBL3103198 0.88 KDM4E (0.43) KDM4EHIF1AEPAS1P2RX7ALDH1A1
SCHEMBL3123352 0.88 KDM4E (0.43) KDM4EHIF1AEPAS1P2RX7ALDH1A1
SCHEMBL6853710 0.86 KDM4E (0.42) KDM4EHIF1AEPAS1P2RX7ALDH1A1
SCHEMBL4309684 0.85 KDM4E (0.46) KDM4EHIF1AEPAS1ALDH1A1ALOX15
SCHEMBL28197969 0.84 LMNA (0.47) KDM4EP2RX7ALDH1A1MAPTHPGD
SCHEMBL15093129 0.84 ALDH1A1 (0.43) KDM4EHIF1AEPAS1ALDH1A1ALOX15
SCHEMBL28477742 0.83 KDM4E (0.43) KDM4EHIF1AEPAS1P2RX7ALDH1A1
Phenol SCHEMBL27448237 0.82 HIF1A (0.45) KDM4EHIF1AEPAS1P2RX7ALDH1A1
SCHEMBL5834020 0.81 KDM4E (0.51) KDM4EHIF1AEPAS1P2RX7ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109642094-B Composite material 巴斯夫欧洲公司 2021-09-14 CN disclosed
CN-108137485-A Process for producing benzoic acid amide compound 爱茉莉太平洋股份有限公司 2018-06-08 CN disclosed
US-20070191585-A1 Organic polymer film and method for forming the same PANASONIC CORPORATION (JP) 2007-08-16 US disclosed