Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8740973 | 0.80 | GPR17 (0.36) | GPR17KMT2AMEN1FABP4HPGD | |
| SCHEMBL27475223 | 0.79 | KDM4E (0.40) | KMT2AMEN1POLBHPGDTSHR | |
| SCHEMBL8437425 | 0.77 | GPR17 (0.40) | GPR17KMT2AMEN1FEN1FABP4 | |
| SCHEMBL6218390 | 0.76 | ALDH1A1 (0.40) | GPR17KMT2AMEN1SPRPOLB | |
| SCHEMBL9136253 | 0.76 | CES2 (0.34) | FEN1POLB | |
| SCHEMBL8013023 | 0.74 | CA1 (0.38) | KMT2AMEN1POLBKDM4E | |
| SCHEMBL9226589 | 0.73 | POLB (0.50) | KMT2AFEN1POLBAPEX1HPGD | |
| SCHEMBL8740970 | 0.72 | MEN1 (0.35) | GPR17KMT2AMEN1SPRPPARG | |
| SCHEMBL30417758 | 0.71 | ERCC5 (0.38) | GPR17KMT2AMEN1FEN1FABP4 | |
| SCHEMBL8435129 | 0.71 | ERCC5 (0.38) | GPR17KMT2AMEN1FEN1FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607942-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |
| US-5416096-A | 7-(1-pyrrolidinyl)-3-quinolone carboxylic acid derivatives as antibacterial agents and feed additives | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-16 | — | — | US | disclosed |
| US-5059597-A | Animal growth regulators; enterobacter | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-22 | — | — | US | disclosed |
| US-4990517-A | 7-(1-pyrrolidinyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives as antibacterial agents and feed additives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |