SCHEMBL9136253

SCHEMBL9136253

O=C(O)CC(=O)c1c(F)c(Cl)c(F)c(F)c1Cl

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
FEN1 P39748 1/20 0.32
LDHA P00338 1/20 0.32
SRR Q9GZT4 1/20 0.32
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8740997 0.76 GPR17 (0.40) FEN1POLB
SCHEMBL8727075 0.75 CES2 (0.41) CES2CES1
SCHEMBL330842 0.75 HTT (0.43) CES2CES1LDHASRR
SCHEMBL9134506 0.70 CES2 (0.41) CES2CES1
SCHEMBL8726566 0.70 CES2 (0.46) CES2CES1
SCHEMBL8433214 0.69 KEAP1 (0.37) CES2CES1FEN1POLB
SCHEMBL8437425 0.69 GPR17 (0.40) FEN1POLB
SCHEMBL20529620 0.69 CES2 (0.50) CES2CES1
SCHEMBL4936537 0.67 CES2 (0.42) CES2CES1
SCHEMBL10406919 0.67 CES2 (0.42) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5464796-A Bactericides and feed additives BAYER AKTIENGESELLSCHAFT (DE) 1995-11-07 US disclosed