Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carisbamate SCHEMBL8741032 | 1.00 | ADRB2 (0.49) | ADRB2ADRB1AOC3CASP1CYP1A2 | |
| Carisbamate SCHEMBL1037665 | 0.95 | AOC3 (0.49) | ADRB2ADRB1AOC3CASP1CYP1A2 | |
| Carisbamate SCHEMBL729003 | 0.95 | AOC3 (0.49) | ADRB2ADRB1AOC3CASP1CYP1A2 | |
| Carisbamate SCHEMBL2425732 | 0.95 | AOC3 (0.49) | ADRB2ADRB1AOC3CASP1CYP1A2 | |
| SCHEMBL13879248 | 0.84 | CASP1 (0.48) | ADRB2ADRB1AOC3CASP1CYP1A2 | |
| SCHEMBL28041733 | 0.84 | CASP1 (0.45) | ADRB2ADRB1AOC3CASP1CYP1A2 | |
| SCHEMBL28041758 | 0.84 | CASP1 (0.45) | ADRB2ADRB1AOC3CASP1CYP1A2 | |
| SCHEMBL28041546 | 0.84 | CASP1 (0.45) | ADRB2ADRB1AOC3CASP1CYP1A2 | |
| SCHEMBL13001768 | 0.83 | CASP1 (0.49) | ADRB2ADRB1AOC3CASP1CYP1A2 | |
| SCHEMBL14200056 | 0.83 | CASP1 (0.49) | ADRB2ADRB1AOC3CASP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698588-A | OPTICALLY PURE ENANTIOMERIC FORM; TREATING CENTRAL NERVOUS SYSTEM DISORDERS | YUKONG LIMITED (KR) | 1997-12-16 | — | — | US | disclosed |