Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28041546 | 1.00 | CASP1 (0.45) | CASP1CYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL28041733 | 1.00 | CASP1 (0.45) | CASP1CYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL27918589 | 0.86 | CASP1 (0.43) | CASP1CYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL27900779 | 0.86 | CASP1 (0.43) | CASP1CYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL27900869 | 0.86 | CASP1 (0.43) | CASP1CYP1A2SMN1; SMN2CYP2D6PKM | |
| Carisbamate SCHEMBL8741086 | 0.84 | ADRB2 (0.49) | CASP1CYP1A2SMN1; SMN2CYP2D6PKM | |
| Carisbamate SCHEMBL8741032 | 0.84 | ADRB2 (0.49) | CASP1CYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL13879248 | 0.83 | CASP1 (0.48) | CASP1CYP1A2SMN1; SMN2CYP2D6PKM | |
| Carisbamate SCHEMBL1037665 | 0.81 | AOC3 (0.49) | CASP1CYP1A2SMN1; SMN2CYP2D6PKM | |
| Carisbamate SCHEMBL2425732 | 0.81 | AOC3 (0.49) | CASP1CYP1A2SMN1; SMN2CYP2D6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111419830-B | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes | 比皮艾思药物研发有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115996905-A | Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases | 生物药品解决方案有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-105209027-A | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes | BIO PHARM SOLUTIONS CO LTD | 2015-12-30 | — | — | CN | disclosed |