Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873598 | 0.80 | LMNA (0.55) | FFAR1LMNAL3MBTL1F2RL1 | |
| SCHEMBL7866230 | 0.75 | CYP4F2 (0.47) | FFAR1LMNA | |
| SCHEMBL10877101 | 0.75 | FFAR1 (0.60) | FFAR1 | |
| SCHEMBL10665281 | 0.75 | FFAR1 (0.60) | FFAR1 | |
| SCHEMBL10665285 | 0.75 | FFAR1 (0.60) | FFAR1 | |
| SCHEMBL2128463 | 0.73 | ALDH1A1 (0.47) | LMNAL3MBTL1 | |
| SCHEMBL362859 | 0.73 | CYP1A2 (0.45) | FFAR1L3MBTL1 | |
| SCHEMBL10613622 | 0.73 | ESR1 (0.52) | TSHRLMNAL3MBTL1 | |
| SCHEMBL5672568 | 0.73 | LTA4H (0.57) | FFAR1LMNA | |
| SCHEMBL16972780 | 0.72 | CYP4F2 (0.62) | FFAR1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619184-A2 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | The Regents of the University of Michigan (US) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012040527-A2 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-03-29 | — | — | WO | disclosed |