Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18538114 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPK1LMNAHTTKMT2A | |
| SCHEMBL13980882 | 0.84 | ALDH1A1 (0.56) | SMN1; SMN2LMNAHTTKMT2AGLA | |
| SCHEMBL9699204 | 0.84 | ALDH1A1 (0.56) | SMN1; SMN2LMNAHTTKMT2AGLA | |
| SCHEMBL9699210 | 0.84 | ALDH1A1 (0.56) | SMN1; SMN2LMNAHTTKMT2AGLA | |
| SCHEMBL19975546 | 0.83 | NPY5R (0.49) | KMT2AACACBGAAGPR88RAB9A | |
| SCHEMBL3014291 | 0.83 | NPY5R (0.49) | KMT2AACACBGAAGPR88RAB9A | |
| SCHEMBL3014293 | 0.83 | NPY5R (0.49) | KMT2AACACBGAAGPR88RAB9A | |
| SCHEMBL18082662 | 0.80 | ACACB (0.57) | KMT2AACACBGPR88RAB9ANPSR1 | |
| SCHEMBL11764494 | 0.80 | ALOX15 (0.51) | LMNAKMT2AGLAALOX15GAA | |
| SCHEMBL850878 | 0.80 | NPSR1 (0.49) | MAPK1LMNAKMT2AACACBGPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603414-B1 | (-)-RITODRINE | MEIJI SEIKA CO (JP) | 1997-02-12 | — | — | EP | disclosed |
| US-5449694-A | Muscle relaxants for threatened premature birth and abortion; dysmenorrhea | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0603414-A1 | (-)-RITODRINE | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1994-06-29 | — | — | EP | disclosed |