Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.56 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RGS12 | O14924 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699204 | 1.00 | ALDH1A1 (0.56) | ALDH1A1ASAH1ACER2ATMLMNA | |
| SCHEMBL13980882 | 1.00 | ALDH1A1 (0.56) | ALDH1A1ASAH1ACER2ATMLMNA | |
| SCHEMBL7783393 | 0.85 | ATM (0.56) | ALDH1A1ATMLMNASMN1; SMN2CYP3A4 | |
| SCHEMBL18538114 | 0.85 | SMN1; SMN2 (0.58) | ALDH1A1ASAH1ACER2ATMLMNA | |
| SCHEMBL8742437 | 0.84 | SMN1; SMN2 (0.50) | ALDH1A1ATMLMNAHTTSMN1; SMN2 | |
| SCHEMBL9698707 | 0.83 | ADRA2C (0.56) | ALDH1A1ASAH1ACER2LMNANPY5R | |
| SCHEMBL9698709 | 0.83 | ADRA2C (0.56) | ALDH1A1ASAH1ACER2LMNANPY5R | |
| SCHEMBL12067906 | 0.83 | ATM (0.47) | ALDH1A1ASAH1ACER2ATMLMNA | |
| SCHEMBL9993761 | 0.83 | ATM (0.47) | ALDH1A1ASAH1ACER2ATMLMNA | |
| SCHEMBL9371027 | 0.82 | MEN1 (0.58) | ALDH1A1ATMHSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079167-A | Enzymatic resolution of amino acid carbamate racemates | GESELLSCHAFT FUR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) (DE) | 1992-01-07 | — | — | US | claimed |