Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | AGXT | P21549 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11991410 | 0.80 | TAAR1 (0.62) | AOC3TAAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL5477927 | 0.78 | TAAR1 (0.56) | AOC3TAAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL267087 | 0.78 | TAAR1 (0.72) | AOC3TAAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL30080050 | 0.76 | TAAR1 (0.77) | AOC3TAAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL723511 | 0.76 | TAAR1 (0.77) | AOC3TAAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL14668122 | 0.74 | CHRM2 (0.59) | AOC3TAAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL44276 | 0.74 | AOC3 (0.75) | AOC3TAAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL18122711 | 0.74 | AOC3 (0.75) | AOC3TAAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL24440174 | 0.73 | TAAR1 (0.53) | TAAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL21002162 | 0.73 | TAAR1 (0.71) | AOC3TAAR1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619174-A1 | PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE | Ind-Swift Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038974-A1 | PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE | IND-SWIFT LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |