SCHEMBL874272

SCHEMBL874272

Cc1cc(C)c2ncccc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMD14 O00487 1/20 0.67
COPS5 Q92905 1/20 0.67
CCR1 P32246 6/20 0.61
CCR8 P51685 6/20 0.61
CCR5 P51681 4/20 0.61
ALDH1A1 P00352 4/20 0.52
DYRK1A Q13627 1/20 0.51
LMNA P02545 3/20 0.50
PRMT5 O14744 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.49
MAPT P10636 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
HTT P42858 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
HPGD P15428 1/20 0.49
MAPK1 P28482 1/20 0.49
SLC40A1 Q9NP59 1/20 0.49
KDM4E B2RXH2 2/20 0.48
GMNN O75496 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL28273126 0.89 ALDH1A1 (0.57) PSMD14COPS5CCR1CCR8CCR5
SCHEMBL12093369 0.82 CCR1 (0.56) PSMD14COPS5CCR1CCR8CCR5
SCHEMBL17691565 0.81 DYRK1A (0.54) PSMD14COPS5CCR1CCR8CCR5
SCHEMBL7450182 0.80 CCR1 (0.55) PSMD14COPS5CCR1CCR8CCR5
SCHEMBL5544307 0.80 CCR1 (0.55) PSMD14COPS5CCR1CCR8CCR5
SCHEMBL3582732 0.80 CCR1 (0.55) PSMD14COPS5CCR1CCR8CCR5
SCHEMBL2938512 0.80 LMNA (0.56) PSMD14COPS5CCR1CCR8CCR5
SCHEMBL5544300 0.80 CCR1 (0.55) PSMD14COPS5CCR1CCR8CCR5
SCHEMBL19001540 0.80 CCR1 (0.55) PSMD14COPS5CCR1CCR8CCR5
SCHEMBL2696188 0.80 PSMD14 (0.62) PSMD14COPS5CCR1CCR8CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119340463-A Long-life wide electrochemical window polymer solid electrolyte and preparation method thereof 浙江智邦锂电新材料有限公司 2025-01-21 CN claimed
CN-119340464-A Novel wide electrochemical window polymer solid electrolyte and preparation method thereof 浙江智邦锂电新材料有限公司 2025-01-21 CN claimed
CN-118667065-A Self-supporting polymer solid electrolyte and preparation method thereof 浙江智邦锂电新材料有限公司 2024-09-20 CN claimed
CN-109438342-A A kind of method that palladium chtalyst 8- methylquinoline derivatives synthesize alpha-keto ester with the dehydrogenation coupling reaction of 2-ketoacid 湘潭大学 2019-03-08 CN claimed
US-9796800-B2 Process for producing polydienes BRIDGESTONE CORPORATION (JP) 2017-10-24 US claimed
US-20160108153-A1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTONE CORPORATION (JP) 2016-04-21 US claimed
CN-103154044-B Process for producing polydienes BRIDGESTONE CO.,LTD. (JP) 2016-02-17 CN claimed
US-9249244-B2 Process for producing polydienes BRIDGESTONE CORPORATION (JP) 2016-02-02 US claimed
EP-2619233-A1 PROCESS FOR PRODUCING POLYDIENES Bridgestone Corporation (JP) 2013-07-31 EP claimed
CN-103154044-A Process for producing polydienes BRIDGESTONE CORP 2013-06-12 CN claimed
WO-2012040026-A1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTONE CORPORATION (JP) 2012-03-29 WO claimed
EP-0505565-A1 QUINOLINE DERIVATIVES, THEIR PRODUCTION AND USE. TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1992-09-30 EP claimed
WO-1991009017-A1 QUINOLINE DERIVATIVES, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-06-27 WO claimed
CN-1039416-A Quinoline and preparation thereof and purposes TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1990-02-07 CN claimed
CN-119340464-A Novel wide electrochemical window polymer solid electrolyte and preparation method thereof 浙江智邦锂电新材料有限公司 2025-01-21 CN disclosed
CN-119340463-A Long-life wide electrochemical window polymer solid electrolyte and preparation method thereof 浙江智邦锂电新材料有限公司 2025-01-21 CN disclosed
CN-118667065-A Self-supporting polymer solid electrolyte and preparation method thereof 浙江智邦锂电新材料有限公司 2024-09-20 CN disclosed
EP-0404941-A1 POLYMERIZED COMPOSITION FOR OBTAINING LUMINESCENT AND SELECTIVE RADIATION-ABSORBENT MATERIALS TOMSKY GOSUDARSTVENNY UNIVERSITET IMENI V.V. KUIBYSHEVA (SU) 1991-01-02 EP disclosed
CN-1037351-A For producing the polymeric constituent that fluoresces and select light-absorbing material UNIV TOMSKY (SU) 1989-11-22 CN disclosed
US-3956420-A CPOLYOLEFIN COMPOSITION FOR ELECTRICAL INSULATIONFERROCENE, 8-SUBSTITUTED QUINOLINE DAINICHI-NIPPON CABLES, LTD. (JA) 1976-05-11 US disclosed