SCHEMBL8742939

SCHEMBL8742939

C=CC(=O)NOS(=O)(=O)C(C)(C)CS(=O)(=O)O

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27967491 0.83 ZDHHC20 (0.33) TSHRZDHHC20ZDHHC2ALDH1A1MAPK1
SCHEMBL28245720 0.82 ZDHHC20 (0.32) TSHRZDHHC20ZDHHC2ALDH1A1MAPK1
Acrylamide SCHEMBL8372871 0.79 ALDH1A1 (0.34) TSHRZDHHC20ZDHHC2ALDH1A1
SCHEMBL128041 0.79 TSHR (0.34) TSHRALDH1A1MAPK1TDP1
SCHEMBL2213304 0.78 TSHR (0.33) TSHRALDH1A1MAPK1TDP1
SCHEMBL18916919 0.78 TSHR (0.33) TSHRALDH1A1MAPK1TDP1
SCHEMBL31350429 0.78 TGM2 (0.35) TSHRALDH1A1MAPK1TDP1
SCHEMBL31350428 0.78 TGM2 (0.35) TSHRALDH1A1MAPK1TDP1
SCHEMBL10714172 0.75 TSHR (0.35) TSHRZDHHC20ZDHHC2ALDH1A1MAPK1
SCHEMBL29192557 0.71 ALDH1A1 (0.38) TSHRZDHHC20ZDHHC2ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5059511-A Curable silicone rubber layer on light sensitive resin of (meth)acryloyl and allyl monomers, photoinitiators FUJI PHOTO FILM CO., LTD. (JP) 1991-10-22 US claimed
EP-0466070-B1 Presensitized plates for use in making lithographic printing plates not requiring dampening with water FUJI PHOTO FILM CO LTD (JP) 1997-01-02 EP disclosed
US-5464686-A Durability FUJI PHOTO FILM CO., LTD. (JP) 1995-11-07 US disclosed
EP-0386777-B1 PS plate for use in making lithographic printing plate requiring no dampening water FUJI PHOTO FILM CO LTD (JP) 1994-02-16 EP disclosed
US-5266443-A Presensitized plates for lithography not requiring dampening with water FUJI PHOTO FILM CO., LTD. (JP) 1993-11-30 US disclosed
US-5252431-A Light sensitive layer and silicone rubber layer; spraying pressurized liquid on the surface to remove the rubber layer FUJI PHOTO FILM CO., LTD. (JP) 1993-10-12 US disclosed
US-5230989-A Presensitized plate FUJI PHOTO FILM CO., LTD. (JP) 1993-07-27 US disclosed
US-5126228-A Presensitized FUJI PHOTO FILM, CO., LTD. (JP) 1992-06-30 US disclosed
EP-0484917-A1 Presensitized plate for use in making lithographic printing plate requiring no damping water FUJI PHOTO FILM CO., LTD. (JP) 1992-05-13 EP disclosed
EP-0475384-A1 Spray development process Fuji Photo Film Co., Ltd. (JP) 1992-03-18 EP disclosed
EP-0466070-A2 Presensitized plates for use in making lithographic printing plates not requiring dampening with water Fuji Photo Film Co., Ltd. (JP) 1992-01-15 EP disclosed
US-5061598-A PRESENSITIZED; DURABILITY, SCRATCH RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1991-10-29 US disclosed
US-5059511-A Curable silicone rubber layer on light sensitive resin of (meth)acryloyl and allyl monomers, photoinitiators FUJI PHOTO FILM CO., LTD. (JP) 1991-10-22 US disclosed
EP-0386777-A2 PS plate for use in making lithographic printing plate requiring no dampening water Fuji Photo Film Co., Ltd. (JP) 1990-09-12 EP disclosed