SCHEMBL8742965

SCHEMBL8742965

C=C(C[N+](C)(C)C)C(=O)Cl

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
APEX1 P27695 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1898329 0.76 TSHR (0.52) TSHRALDH1A1LMNAAPEX1
SCHEMBL7791560 0.75 ACHE (0.39) TSHRALDH1A1LMNA
Hydrochloric Acid SCHEMBL8616930 0.74 ALDH1A1 (0.55) TSHRALDH1A1LMNAAPEX1
Bromide SCHEMBL22034719 0.74 TSHR (0.50) TSHRALDH1A1LMNAAPEX1
Hydrochloric Acid SCHEMBL2399401 0.74 TSHR (0.50) TSHRALDH1A1LMNAAPEX1
SCHEMBL15327604 0.74 TSHR (0.43) TSHRALDH1A1LMNAAPEX1
SCHEMBL434755 0.74 TSHR (0.43) TSHRALDH1A1LMNAAPEX1
Hydrochloric Acid SCHEMBL2399402 0.72 TSHR (0.42) TSHRALDH1A1LMNAAPEX1
SCHEMBL1642927 0.72 ACHE (0.52) TSHRLMNAAPEX1
SCHEMBL27522337 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0751405-A2 Balanced charge polymer and hydrophilic contact lens manufactured therefrom Hydron Limited (GB) 1997-01-02 EP claimed
EP-0751404-A2 Balanced charge polymer and hydrophilic contact lens manufactured therefrom Hydron Limited (GB) 1997-01-02 EP claimed
US-5391669-A Lens formed of water swellable crosslinked polymer containing polymer containing cationic-aninoic pair of unsaturated monomers and nonionic monomers HYDRON LIMITED (GB) 1995-02-21 US claimed
EP-0563299-A4 BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM CESKOSLOVENSKA AKADEMIE VED (CS) 1994-07-20 EP claimed
US-5270415-A Balanced charge polymer and hydrophilic contact lens manufactured therefrom ALLERGAN INC. (US) 1993-12-14 US claimed
EP-0563299-A1 BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM Hydron Limited (GB) 1993-10-06 EP claimed
WO-1992011301-A1 BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM ALLERGAN, INC. (US) 1992-07-09 WO claimed
JP-4241873-A None JP disclosed
CN-106538074-A Method and system for fabricating cross-layer pattern 斯特拉塔西斯公司 2017-03-22 CN disclosed
US-5271765-A Aqueous cationic dye-based ink jet inks E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-12-21 US disclosed
JP-H04241873-A HEPARIN REMOVING METHOD AND DEVICE THEREOF PALL CORP 1992-08-28 JP disclosed