⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76560 | 0.81 | LMNA (0.32) | — | |
| SCHEMBL2859593 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL7459719 | 0.79 | PABPC1 (0.32) | — | |
| SCHEMBL11224081 | 0.78 | LMNA (0.33) | — | |
| Hydrochloric Acid SCHEMBL6979205 | 0.78 | — | — | |
| SCHEMBL1946653 | 0.77 | KMT2A (0.38) | — | |
| SCHEMBL3984911 | 0.77 | KMT2A (0.36) | — | |
| SCHEMBL13719990 | 0.77 | — | — | |
| SCHEMBL76934 | 0.77 | MEN1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL5076344 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103288824-B | Tetrahydropyridine Pyridione derivatives, its preparation method and application | SHANGHAI NORMAL UNIVERSITY (CN) | 2015-12-09 | — | — | CN | claimed |
| CN-103288824-A | Tetrahydropyridopyridone derivative as well as preparation method and application thereof | UNIV SHANGHAI | 2013-09-11 | — | — | CN | claimed |
| WO-2008005423-A1 | IMPROVED METHOD OF MAKING SUFENTANIL | CAMBREX CHARLES CITY, INC. (US) | 2008-01-10 | — | — | WO | claimed |
| EP-1453824-A1 | NEW GENERATION TRIPLE-TARGETING, CHIRAL, BROAD-SPECTRUM ANTIMICROBIAL 7-SUBSTITUTED PIPERIDINO-QUINOLONE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION, COMPOSITIONS AND USE AS MEDICAMENTS | Wockhardt Limited (IN) | 2004-09-08 | — | — | EP | claimed |
| WO-2003050107-A1 | NEW GENERATION TRIPLE-TARGETING, CHIRAL, BROAD-SPECTRUM ANTIMICROBIAL 7-SUBSTITUTED PIPERIDINO-QUINOLONE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION, COMPOSITIONS AND USE AS MEDICAMENTS | WOCKHARDT LIMITED (IN) | 2003-06-19 | — | — | WO | claimed |
| US-20240317774-A1 | Pharmaceutical Compound | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2024-09-26 | — | — | US | disclosed |
| EP-4355750-A1 | PHARMACEUTICAL COMPOUND | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2024-04-24 | — | — | EP | disclosed |
| CN-117480172-A | Pharmaceutical compounds | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-01-30 | — | — | CN | disclosed |
| WO-2023278843-A2 | SOLID FORMS OF OSANETANT | ACER THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
| WO-2022263557-A1 | PHARMACEUTICAL COMPOUND | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-12-22 | — | — | WO | disclosed |
| EP-3807269-A1 | NEW ISOXAZOLYL ETHER DERIVATIVES AS GABA A ALPHA5 PAM | F. Hoffmann-La Roche AG (CH) | 2021-04-21 | — | — | EP | disclosed |
| WO-2019238633-A1 | NEW ISOXAZOLYL ETHER DERIVATIVES AS GABA A ALPHA5 PAM | F. HOFFMANN-LA ROCHE AG (CH) | 2019-12-19 | — | — | WO | disclosed |
| US-4410536-A | 7,8,9,10-Tetrahydrothieno[3,2-e]pyrido[4,3-b]indole compounds and their anti-depressant use | TROPONWERKE GMBH & CO. K.G. (DE) | 1983-10-18 | — | — | US | disclosed |
| EP-0083093-A2 | Process and intermediates of octahydrobenzofuro(3,2-e)isoquinolines | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-07-06 | — | — | EP | disclosed |
| EP-0062873-A1 | 1-Substituted-4-phenyl-polyhydro-pyridines and -pyrrolidines, processes for their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1982-10-20 | — | — | EP | disclosed |
| EP-0012347-B1 | 7,8,9,10-TETRAHYDROTHIENO(3,2-E)PYRIDO(4,3-B)INDOLES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Troponwerke GmbH & Co. KG (DE) | 1982-07-28 | — | — | EP | disclosed |
| EP-0029707-A1 | Novel piperidine derivatives, method for the preparation thereof and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD (JP) | 1981-06-03 | — | — | EP | disclosed |
| EP-0012347-A1 | 7,8,9,10-Tetrahydrothieno(3,2-e)pyrido(4,3-b)indoles, process for their preparation and medicaments containing them | Troponwerke GmbH & Co. KG (DE) | 1980-06-25 | — | — | EP | disclosed |
| EP-0007067-A1 | Phenylpiperidine derivatives, processes for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1980-01-23 | — | — | EP | disclosed |
| EP-0004358-A1 | N-oxacyclylalkyl piperidines, process for their preparation, pharmaceutical compositions containing these compounds | CIBA-GEIGY AG (CH) | 1979-10-03 | — | — | EP | disclosed |