Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7459719 | 0.98 | PABPC1 (0.32) | LMNAPABPC1APOBEC3AEIF4HAPOBEC3G | |
| SCHEMBL11224081 | 0.97 | LMNA (0.33) | LMNAHTT | |
| SCHEMBL1828313 | 0.92 | LMNA (0.33) | LMNA | |
| SCHEMBL7074888 | 0.84 | ALDH1A1 (0.39) | ALDH1A1HPGD | |
| SCHEMBL874303 | 0.81 | — | — | |
| SCHEMBL9051047 | 0.78 | CYP1A2 (0.44) | LMNAHTTALDH1A1HPGDKMT2A | |
| SCHEMBL1977562 | 0.76 | LMNA (0.31) | LMNA | |
| SCHEMBL5392162 | 0.76 | ORAI1 (0.38) | LMNAKMT2A | |
| SCHEMBL13719990 | 0.76 | — | — | |
| SCHEMBL1946653 | 0.76 | KMT2A (0.38) | LMNAHTTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110128325-B | Substituted phenyl piperidone compound and synthesis method and application thereof | 广州医科大学 | 2021-01-05 | — | — | CN | claimed |
| CN-109880130-A | A kind of mercaptan-alkene visible light emulsion polymerization prepares the method and its dual responsiveness nanosphere of dual responsiveness nanosphere | 贵州民族大学 | 2019-06-14 | — | — | CN | claimed |
| CN-108622866-A | The method and its application of black phosphorus are thinned in a kind of wet chemical | 天津大学 | 2018-10-09 | — | — | CN | claimed |
| US-20160031817-A1 | 3-PIPERIDONE COMPOUNDS AND THEIR USE AS NEUROKININ-1 (NK1) RECEPTOR ANTAGONISTS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-02-04 | — | — | US | claimed |
| CN-105209436-A | 3-piperidone compounds and their use as neurokinin-1 (NK1) receptor antagonists | UNIV NANYANG TECH | 2015-12-30 | — | — | CN | claimed |
| WO-2014142761-A1 | 3-PIPERIDONE COMPOUNDS AND THEIR USE AS NEUROKININ-1 (NK1) RECEPTOR ANTAGONISTS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-09-18 | — | — | WO | claimed |
| EP-2318363-A1 | HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS | Nuevolution A/S (DK) | 2011-05-11 | — | — | EP | claimed |
| WO-2009152824-A1 | HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS | NUEVOLUTION A/S (DK) | 2009-12-23 | — | — | WO | claimed |
| US-6388083-B2 | ANTAGONIST TO SUBSTANCE P RECEPTORS | MERCK & CO., INC. | 2002-05-14 | — | — | US | claimed |
| US-20020019532-A1 | Process for the synthesis of (2S)-phenyl-3-piperidone | MERCK & CO., INC. | 2002-02-14 | — | — | US | claimed |
| EP-0786483-B1 | Process for an activated anionic lactam polymerisation | INVENTA AG (CH) | 2000-04-19 | — | — | EP | claimed |
| EP-0897303-A4 | — | — | 1999-02-24 | — | — | EP | claimed |
| EP-0897303-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-02-24 | — | — | EP | claimed |
| EP-0853617-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | Novartis AG (CH) | 1998-07-22 | — | — | EP | claimed |
| WO-1997036605-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | claimed |
| EP-0786483-A2 | Process for an activated anionic lactam polymerisation | EMS-INVENTA AG (CH) | 1997-07-30 | — | — | EP | claimed |
| WO-1997008155-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | claimed |
| US-11964943-B2 | 3,5-diarylidenyl-n-substituted-piperid-4-one-derived inhibitors of Stat3 pathway activity and uses thereof | KIAKOS KONSTANTINOS (AT) | 2024-04-23 | — | — | US | disclosed |
| US-4115433-A | RHODIUM CARBONYL SULFUR CLUSTER COMPOUND | UNION CARBIDE CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
| US-3944588-A | RHODIUM CARBONYL, TRIALKANOLAMINE BORATE | UNION CARBIDE CORPORATION (US) | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11964943-B2 | 3,5-diarylidenyl-n-substituted-piperid-4-one-derived inhibitors of Stat3 pathway activity and uses thereof | STAT3, JAK2, STAT6 | LMNA 3396/4885PABPC1 922/4885APOBEC3A 2928/4885 |
| US-20020019532-A1 | Process for the synthesis of (2S)-phenyl-3-piperidone | DHPS, NPEPPS, ALDH18A1 | LMNA 3683/4885PABPC1 1381/4885APOBEC3A 2576/4885 |
| US-20160031817-A1 | 3-PIPERIDONE COMPOUNDS AND THEIR USE AS NEUROKININ-1 (NK1) RECEPTOR ANTAGONISTS | TACR1, NPSR1, TACR2 | LMNA 4098/4885PABPC1 1433/4885APOBEC3A 3440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.