Bicarbonate

Bicarbonate

SCHEMBL8743136

Cl.NC1CC1.O=C(O)O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL7136153 0.96 GABRR1 (0.42)
Bicarbonate SCHEMBL7136582 0.96 GABRR1 (0.42)
Bicarbonate SCHEMBL1702507 0.96
Bicarbonate SCHEMBL11593113 0.93 PEPD (0.41)
Bicarbonate SCHEMBL578685 0.89
Acetic Acid SCHEMBL27585800 0.86
Cyclopentanamine SCHEMBL578697 0.86 THRB (0.39)
Oxalic Acid SCHEMBL27895423 0.85 GABRR1 (0.40)
Cycloheptanamine SCHEMBL720218 0.83 CES2 (0.43)
Cyclohexylamine SCHEMBL974340 0.83 CES2 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623360-B1 PRODUCTION METHOD FOR 1 AMINO CYCLOPROPANE CARBOXYLIC ACID NONHYDRATE SUMITOMO CHEMICAL CO (JP) 2021-12-29 EP claimed
EP-3636630-B1 PRODUCTION METHOD FOR 1 AMINO CYCLOPROPANE CARBOXYLIC ACID NONHYDRATE SUMITOMO CHEMICAL CO (JP) 2021-12-15 EP claimed
EP-0676390-B1 Process for the preparation of 1-aminocyclopropane carboxylic acid hydrochloride HUELS CHEMISCHE WERKE AG (DE) 1997-01-02 EP claimed
EP-0676390-A1 Process for the preparation of 1-aminocyclopropane carboxylic acid hydrochloride HÜLS AKTIENGESELLSCHAFT (DE) 1995-10-11 EP claimed
WO-1997040007-A1 2,3,5,6-TETRAFLUOROBENZOIC ACID AMIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-10-30 WO disclosed
EP-0676390-B1 Process for the preparation of 1-aminocyclopropane carboxylic acid hydrochloride HUELS CHEMISCHE WERKE AG (DE) 1997-01-02 EP disclosed
EP-0676390-B1 Process for the preparation of 1-aminocyclopropane carboxylic acid hydrochloride HUELS CHEMISCHE WERKE AG (DE) 1997-01-02 EP disclosed
EP-0676390-A1 Process for the preparation of 1-aminocyclopropane carboxylic acid hydrochloride HÜLS AKTIENGESELLSCHAFT (DE) 1995-10-11 EP disclosed
EP-0676390-A1 Process for the preparation of 1-aminocyclopropane carboxylic acid hydrochloride HÜLS AKTIENGESELLSCHAFT (DE) 1995-10-11 EP disclosed
EP-0676390-A1 Process for the preparation of 1-aminocyclopropane carboxylic acid hydrochloride HÜLS AKTIENGESELLSCHAFT (DE) 1995-10-11 EP disclosed
EP-0346709-B1 USE OF ACYLATE -AMINOACIDESTER DERIVATES AS INSECT AND MITE REPELLENT BAYER AG (DE) 1992-11-19 EP disclosed
EP-0221502-A1 Substituted 1-aminocyclopropane carboxylic-acid derivatives BAYER AG (DE) 1987-05-13 EP disclosed
EP-0057357-B1 PLANT GROWTH STUNTING AGENT BAYER AG (DE) 1984-07-25 EP disclosed
EP-0057357-A2 Plant growth stunting agent BAYER AG (DE) 1982-08-11 EP disclosed
EP-0025141-B1 PROCESS FOR THE PRODUCTION OF 1-AMINO-CYCLOPROPANE-CARBOXYLIC ACID AND ITS DERIVATIVES BAYER AG (DE) 1982-05-12 EP disclosed
EP-0005782-B1 PLANT GROWTH REGULANTS AND COMPOSITIONS CONTAINING THEM, THEIR APPLICATION AND THEIR PREPARATION BAYER AG (DE) 1982-02-24 EP disclosed
EP-0025141-A1 Process for the production of 1-amino-cyclopropane-carboxylic acid and its derivatives BAYER AG (DE) 1981-03-18 EP disclosed