Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16371856 | 0.98 | PRMT1 (0.45) | SMN1; SMN2TSHRPRMT1ZDHHC20ZDHHC2 | |
| SCHEMBL8743224 | 0.94 | TSHR (0.39) | SMN1; SMN2TSHRPRMT1ZDHHC20ZDHHC2 | |
| SCHEMBL8743227 | 0.85 | TSHR (0.39) | SMN1; SMN2TSHRZDHHC20ZDHHC2MAPT | |
| SCHEMBL8529030 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2TSHRPRMT1ZDHHC20ZDHHC2 | |
| SCHEMBL6557587 | 0.79 | ALDH1A1 (0.50) | SMN1; SMN2TSHRMAPTALDH1A1MAPK1 | |
| SCHEMBL18614766 | 0.78 | ZDHHC20 (0.64) | TSHRPRMT1ZDHHC20ZDHHC2MAPT | |
| SCHEMBL19126158 | 0.78 | TSHR (0.40) | SMN1; SMN2TSHRPRMT1ZDHHC20ZDHHC2 | |
| SCHEMBL9445381 | 0.78 | HDAC3 (0.46) | ZDHHC20ZDHHC2MEN1KMT2AEPHX2 | |
| SCHEMBL23631357 | 0.77 | TSHR (0.48) | SMN1; SMN2TSHRMAPTALDH1A1MEN1 | |
| SCHEMBL22492168 | 0.77 | TSHR (0.48) | SMN1; SMN2TSHRMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751119-A1 | A process for preparing acryloyl carbamates or ureas | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |