Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8743250 | 1.00 | RIPK1 (0.49) | RIPK1ALDH1A1LMNACHRNB2CHRNB4 | |
| SCHEMBL27382463 | 0.85 | RIPK1 (0.47) | RIPK1LMNACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3980676 | 0.85 | MTNR1A (0.53) | ALDH1A1LMNACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL1649360 | 0.84 | RIPK1 (0.46) | RIPK1LMNACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13801021 | 0.83 | HPGD (0.44) | RIPK1LMNACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL20885187 | 0.82 | ALDH1A1 (0.47) | RIPK1ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL4781947 | 0.82 | ALDH1A1 (0.47) | RIPK1ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18548754 | 0.82 | SMN1; SMN2 (0.56) | RIPK1LMNACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL10362252 | 0.81 | ALDH1A1 (0.50) | RIPK1ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL5566856 | 0.81 | ALDH1A1 (0.50) | RIPK1ALDH1A1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751113-A1 | Optically active phenol derivatives and preparation thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5420363-A | Catalytic reaction of phenol with secondary carbinol for enantiomorphs | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| US-5354913-A | Chemical intermediates for drugs or drugs as thromboxane, prostaglandin antagonist, lipoxygenase enzyme inhibitor, antioxidants | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0582382-A2 | Optically active phenol derivatives and preparation thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-02-09 | — | — | EP | disclosed |