Fluoride Ion

Fluoride Ion

SCHEMBL8743248

[B+3].[F-].[F-].[F-].[F-].c1ccc(-c2cc(-c3ccccc3)[o+]c(-c3ccccc3)c2)cc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
CRHBP P24387 2/20 0.38
CRHR2 Q13324 2/20 0.38
MAOA P21397 1/20 0.36
MAPK1 P28482 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
NOTUM Q6P988 1/20 0.35
MMP3 P08254 1/20 0.35
BCL2L1 Q07817 1/20 0.35
ALOX5 P09917 1/20 0.34
BACE1 P56817 1/20 0.33
AKT1 P31749 1/20 0.33
AKT2 P31751 1/20 0.33
KDM4E B2RXH2 2/20 0.32
HTT P42858 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL596786 0.95 ALDH1A1 (0.50) ALDH1A1CRHBPCRHR2MAOAMAPK1
Fluoride SCHEMBL8743255 0.93 ALDH1A1 (0.43) ALDH1A1CRHBPCRHR2MAOAMAPK1
Iodide SCHEMBL7170134 0.92 ALDH1A1 (0.47) ALDH1A1CRHBPCRHR2MAOAMAPK1
SCHEMBL29968018 0.92 ALDH1A1 (0.47) ALDH1A1CRHBPCRHR2MAOAMAPK1
Hydrochloric Acid SCHEMBL9574779 0.92 ALDH1A1 (0.47) ALDH1A1CRHBPCRHR2MAOAMAPK1
SCHEMBL12266121 0.92 ALDH1A1 (0.47) ALDH1A1CRHBPCRHR2MAOAMAPK1
SCHEMBL7948022 0.88 ALDH1A1 (0.43) ALDH1A1CRHBPCRHR2MAOAMAPK1
SCHEMBL10624682 0.88 ALDH1A1 (0.43) ALDH1A1CRHBPCRHR2MAOAMAPK1
SCHEMBL7933978 0.88 ALDH1A1 (0.43) ALDH1A1CRHBPCRHR2MAOAMAPK1
SCHEMBL345864 0.88 ALDH1A1 (0.43) ALDH1A1CRHBPCRHR2MAOAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0484752-B1 Photopolymerizable composition and photosensitive lithographic printing plate NIPPON PAINT CO LTD (JP) 1997-01-02 EP disclosed
EP-0484752-A1 Photopolymerizable composition and photosensitive lithographic printing plate Nippon Paint Co., Ltd. (JP) 1992-05-13 EP disclosed