Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.57 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | GGT1 | P19440 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27618392 | 0.89 | PTGS2 (0.47) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL338196 | 0.84 | PTGS2 (0.68) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL29432883 | 0.84 | PTGS2 (0.68) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL12469090 | 0.83 | KDM4E (0.40) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL6699052 | 0.83 | MAPK1 (0.49) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL57099 | 0.82 | GRM4 (0.44) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL29549932 | 0.82 | GRM4 (0.44) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL6198267 | 0.82 | MAPK1 (0.47) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL27791867 | 0.82 | MAPK1 (0.47) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL16335017 | 0.82 | ACHE (0.59) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4267633-A1 | LOW DISPERSITY POLYMERS AS A RESULT OF NEAR INFRARED LIGHT INITIATION AND AN IRON CATALYST | Phosuma Photonic & Sustainable Materials GmbH (DE) | 2023-11-01 | — | — | EP | claimed |
| WO-2022165777-A1 | MICRO-NANO STRUCTURE-BASED SUPER-HYDROPHOBIC FABRIC AND PREPARATION METHOD THEREFOR | 苏州大学 | 2022-08-11 | — | — | WO | claimed |
| CN-114751860-A | Synthesis method of nuciferine or nuciferine derivative, nuciferine derivative and application of nuciferine derivative | 华侨大学 | 2022-07-15 | — | — | CN | claimed |
| WO-2022136292-A1 | LOW DISPERSITY POLYMERS AS A RESULT OF NEAR INFRARED LIGHT INITIATION AND AN IRON CATALYST | PHOSUMA PHOTONIC & SUSTAINABLE MATERIALS GMBH (DE) | 2022-06-30 | — | — | WO | claimed |
| CN-114605286-A | Preparation method and application of Perampanel intermediate | 山东达因海洋生物制药股份有限公司 | 2022-06-10 | — | — | CN | claimed |
| CN-102977098-B | Aryl-substituted indolizine derivative and preparation method and applications thereof | UNIV SHAOXING | 2015-04-01 | — | — | CN | claimed |
| CN-102977098-A | Aryl-substituted indolizine derivative and preparation method and applications thereof | UNIV SHAOXING | 2013-03-20 | — | — | CN | claimed |
| CN-101380317-A | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV (CN) | 2009-03-11 | — | — | CN | claimed |
| US-4307034-A | ALKYLATION | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-12-22 | — | — | US | claimed |
| CN-114984003-B | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2024-08-27 | — | — | CN | disclosed |
| US-20240246904-A1 | FUNCTIONALIZED N,N-DIALKYLAMINO PHENYL ETHERS AND THEIR METHOD OF USE | UNIV TEMPLE (US) | 2024-07-25 | — | — | US | disclosed |
| CN-115054600-B | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2024-06-14 | — | — | CN | disclosed |
| US-20240166646-A1 | 1H-PYRROLO[2,3-B]PYRIDINE DERIVATIVES AS BCL-2 INHIBITORS FOR THE TREATMENT OF NEOPLASTIC AND AUTOIMMUNE DISEASES | NEWAVE PHARMACEUTICAL INC. | 2024-05-23 | — | — | US | disclosed |
| WO-2024061340-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2024-03-28 | — | — | WO | disclosed |
| CN-1021009-C | FUNGICIDES | ICI PLC (GB) | 1993-06-02 | — | — | CN | disclosed |
| CN-1020106-C | Process for pyrimidine derivatives | HOFFMANN LA ROCHE (CH) | 1993-03-17 | — | — | CN | disclosed |
| CN-1032782-A | Bactericide | ICI PLC (GB) | 1989-05-10 | — | — | CN | disclosed |
| EP-0307103-A2 | Fungicides | ZENECA LIMITED (GB) | 1989-03-15 | — | — | EP | disclosed |
| CN-87105758-A | Pyrimidine derivatives, their production and use | — | 1988-03-02 | — | — | CN | disclosed |
| US-4307034-A | ALKYLATION | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166646-A1 | 1H-PYRROLO[2,3-B]PYRIDINE DERIVATIVES AS BCL-2 INHIBITORS FOR THE TREATMENT OF NEOPLASTIC AND AUTOIMMUNE DISEASES | BCL2, BCL3, BCL2L1 | PTGS2 109/4885KDM4E 1356/4885HSD17B10 3551/4885 |
| US-20240246904-A1 | FUNCTIONALIZED N,N-DIALKYLAMINO PHENYL ETHERS AND THEIR METHOD OF USE | GAA, GBA1, GBA2 | PTGS2 4166/4885KDM4E 841/4885HSD17B10 2878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.