Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL590788 | 0.79 | TDP1 (0.48) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL30389399 | 0.76 | USP2 (0.44) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL9752063 | 0.74 | CYP1A1 (0.38) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL8767788 | 0.71 | NPC1 (0.48) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL8991877 | 0.71 | ALDH1A1 (0.46) | MEN1KMT2ATDP1LMNAALDH1A1 | |
| SCHEMBL8747000 | 0.71 | CYP1A1 (0.35) | CDK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8589093 | 0.70 | GPR35 (0.33) | TDP1ALDH1A1GAACYP1A1TSHR | |
| SCHEMBL8743296 | 0.70 | TDP1 (0.48) | AURKAPIM1CDK2GSK3BNPC1 | |
| SCHEMBL9305341 | 0.70 | PDPK1 (0.45) | AURKAPIM1CDK2GSK3BNPC1 | |
| SCHEMBL2108122 | 0.69 | CYP1A1 (0.36) | NPC1RAB9AMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616697-A | THIAZOLYL RING CONTAINS A SUBSTITUENT SELECTED FORM HYDROXY, ALKOXY, CYCLOALKOXY, ARYLOXY, MERCAPTO, THIOALKYL, THIOCYCLOALKYL AND THIOARYL AT 4-POSITION | AGFA-GEVAERT, N.V. (BE) | 1997-04-01 | — | — | US | claimed |
| EP-0581342-B1 | Dye-donor element for use according to thermal dye sublimation transfer | AGFA GEVAERT NV (BE) | 1997-01-02 | — | — | EP | claimed |
| EP-0579299-B1 | Black colored dye mixture for use according to thermal dye sublimation transfer | AGFA GEVAERT NV (BE) | 1997-01-02 | — | — | EP | claimed |
| EP-0578870-B1 | Thiazolylazoaniline dyes for use in thermal dye sublimation transfer | AGFA GEVAERT NV (BE) | 1996-12-11 | — | — | EP | claimed |
| US-5476746-A | For recording hard copies of medical diagnostic images that behave visually as metallic silver | AGFA-GEVAERT, N.V. (BE) | 1995-12-19 | — | — | US | claimed |
| US-5432040-A | Colorfast | AGFA-GEVAERT, N.V. (BE) | 1995-07-11 | — | — | US | claimed |
| US-5366951-A | Support with dye donor elements or dye receiver elements | AGFA-GEVAERT, N.V. (BE) | 1994-11-22 | — | — | US | claimed |
| EP-0581342-A1 | Dye-donor element for use according to thermal dye sublimation transfer | AGFA-GEVAERT N.V. (BE) | 1994-02-02 | — | — | EP | claimed |
| EP-0578870-A1 | Thiazolylazoaniline dyes for use in thermal dye sublimation transfer | AGFA-GEVAERT N.V. (BE) | 1994-01-19 | — | — | EP | claimed |
| EP-0579299-A1 | Black colored dye mixture for use according to thermal dye sublimation transfer | AGFA-GEVAERT N.V. (BE) | 1994-01-19 | — | — | EP | claimed |
| JP-6072056-A | — | — | None | — | — | JP | disclosed |
| JP-6092045-A | — | — | None | — | — | JP | disclosed |
| US-5616697-A | THIAZOLYL RING CONTAINS A SUBSTITUENT SELECTED FORM HYDROXY, ALKOXY, CYCLOALKOXY, ARYLOXY, MERCAPTO, THIOALKYL, THIOCYCLOALKYL AND THIOARYL AT 4-POSITION | AGFA-GEVAERT, N.V. (BE) | 1997-04-01 | — | — | US | disclosed |
| US-5616697-A | THIAZOLYL RING CONTAINS A SUBSTITUENT SELECTED FORM HYDROXY, ALKOXY, CYCLOALKOXY, ARYLOXY, MERCAPTO, THIOALKYL, THIOCYCLOALKYL AND THIOARYL AT 4-POSITION | AGFA-GEVAERT, N.V. (BE) | 1997-04-01 | — | — | US | disclosed |
| US-5616697-A | THIAZOLYL RING CONTAINS A SUBSTITUENT SELECTED FORM HYDROXY, ALKOXY, CYCLOALKOXY, ARYLOXY, MERCAPTO, THIOALKYL, THIOCYCLOALKYL AND THIOARYL AT 4-POSITION | AGFA-GEVAERT, N.V. (BE) | 1997-04-01 | — | — | US | disclosed |
| EP-0581342-A1 | Dye-donor element for use according to thermal dye sublimation transfer | AGFA-GEVAERT N.V. (BE) | 1994-02-02 | — | — | EP | disclosed |
| EP-0578870-A1 | Thiazolylazoaniline dyes for use in thermal dye sublimation transfer | AGFA-GEVAERT N.V. (BE) | 1994-01-19 | — | — | EP | disclosed |
| EP-0578870-A1 | Thiazolylazoaniline dyes for use in thermal dye sublimation transfer | AGFA-GEVAERT N.V. (BE) | 1994-01-19 | — | — | EP | disclosed |
| EP-0578870-A1 | Thiazolylazoaniline dyes for use in thermal dye sublimation transfer | AGFA-GEVAERT N.V. (BE) | 1994-01-19 | — | — | EP | disclosed |
| EP-0579299-A1 | Black colored dye mixture for use according to thermal dye sublimation transfer | AGFA-GEVAERT N.V. (BE) | 1994-01-19 | — | — | EP | disclosed |