Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BCL6 | P41182 | 1/20 | 0.40 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21051836 | 0.81 | ALDH1A1 (0.58) | VCAM1ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL6819387 | 0.79 | KMT2A (0.59) | VCAM1ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL26687977 | 0.79 | VCAM1 (0.57) | VCAM1ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL27645487 | 0.79 | VCAM1 (0.49) | VCAM1ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL4054501 | 0.78 | VCAM1 (0.64) | VCAM1ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL12515174 | 0.76 | VCAM1 (0.53) | VCAM1ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL22271642 | 0.76 | VCAM1 (0.53) | VCAM1ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL16050141 | 0.76 | VCAM1 (0.53) | VCAM1ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL73860 | 0.76 | VCAM1 (0.70) | VCAM1ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL10880668 | 0.75 | VCAM1 (0.64) | VCAM1ALDH1A1LMNAGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |