Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22271642 | 0.85 | VCAM1 (0.53) | VCAM1RECQLLMNAGAAALDH1A1 | |
| SCHEMBL26687977 | 0.80 | VCAM1 (0.57) | VCAM1RECQLLMNAGAAALDH1A1 | |
| SCHEMBL27666607 | 0.79 | KDM4E (0.41) | RECQLLMNAGAAALDH1A1MAPT | |
| SCHEMBL874344 | 0.79 | VCAM1 (0.55) | VCAM1RECQLLMNAGAAALDH1A1 | |
| SCHEMBL21051856 | 0.78 | SMN1; SMN2 (0.60) | VCAM1RECQLLMNAGAAALDH1A1 | |
| SCHEMBL21051836 | 0.78 | ALDH1A1 (0.58) | VCAM1RECQLLMNAGAAALDH1A1 | |
| SCHEMBL6819387 | 0.77 | KMT2A (0.59) | VCAM1RECQLLMNAGAAALDH1A1 | |
| SCHEMBL11630929 | 0.76 | LMNA (0.50) | VCAM1RECQLLMNAGAAALDH1A1 | |
| SCHEMBL22271446 | 0.76 | VCAM1 (0.49) | VCAM1RECQLLMNAGAAALDH1A1 | |
| SCHEMBL16050141 | 0.76 | VCAM1 (0.53) | VCAM1RECQLLMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1882586-A | 1H-imidazo[4,5-C]quinoline derivatives in the treatment of protein kinase dependent diseases | NOVARTIS AG (CH) | 2006-12-20 | — | — | CN | disclosed |