Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | RECQL | P46063 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | BLM | P54132 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | APEX1 | P27695 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.53 |
| ▸ | RGS12 | O14924 | 2/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8743681 | 0.84 | EGFR (0.59) | MAPTALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL19895348 | 0.84 | EGFR (0.59) | MAPTALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL21457670 | 0.79 | EGFR (0.58) | ALDH1A1KDM4EKMT2AHPGDCYP3A4 | |
| SCHEMBL21457666 | 0.79 | EGFR (0.58) | ALDH1A1KDM4EKMT2AHPGDCYP3A4 | |
| SCHEMBL8830518 | 0.76 | MAPT (0.55) | MAPTALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL8830519 | 0.76 | MAPT (0.55) | MAPTALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL8830515 | 0.76 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL8830513 | 0.76 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL10517794 | 0.75 | TRPA1 (0.53) | MAPTALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL8830690 | 0.75 | MAPT (0.54) | MAPTALDH1A1KDM4ETDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750498-A1 | USE OF ANTAGONISTS OF EGF OR TGF-ALPHA FOR THE TREATMENT AND PROPHYLAXIS OF ACNE | UNILEVER PLC (GB) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995024896-A2 | USE OF ANTAGONISTS OF EGF OR TGF-ALPHA FOR THE TREATMENT AND PROPHYLAXIS OF ACNE | UNILEVER PLC (GB) | 1995-09-21 | — | — | WO | disclosed |