SCHEMBL8743759

SCHEMBL8743759

N[C@@H](CCCCNC(=O)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
OTC P00480 1/20 0.36
DPP8 Q6V1X1 2/20 0.35
DPP7 Q9UHL4 2/20 0.35
GSR P00390 1/20 0.35
DDAH1 O94760 3/20 0.34
ANPEP P15144 1/20 0.34
ACHE P22303 3/20 0.33
DPP4 P27487 1/20 0.33
DPP9 Q86TI2 1/20 0.33
SLC1A3 P43003 1/20 0.33
SLC1A1 P43005 1/20 0.33
ARG2 P78540 4/20 0.33
ARG1 P05089 3/20 0.33
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8743764 1.00 OTC (0.36) OTCDPP8DPP7GSRDDAH1
SCHEMBL25899125 0.85 ACHE (0.44) ACHEMEN1KMT2A
SCHEMBL31711117 0.77 OTC (0.42) OTCDPP8DPP7GSRDDAH1
SCHEMBL24945952 0.76 GSR (0.53) OTCDPP8DPP7GSRDDAH1
SCHEMBL18924694 0.76 GSR (0.53) OTCDPP8DPP7GSRDDAH1
SCHEMBL22375753 0.76 GSR (0.53) OTCDPP8DPP7GSRDDAH1
SCHEMBL23607693 0.75 ACHE (0.53) DPP7ACHE
SCHEMBL23608137 0.75 ACHE (0.53) DPP7ACHE
SCHEMBL23385458 0.75 ACHE (0.53) DPP7ACHE
SCHEMBL20192789 0.75 GSR (0.56) OTCDPP8DPP7GSRDDAH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0725056-B1 Perfluoroalkylated derivatives of lysine, process for their preparation, their use especially in cosmetics and compositions containing them OREAL (FR) 1997-01-15 EP claimed