Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23608137 | 1.00 | ACHE (0.53) | ACHEDPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL23607693 | 1.00 | ACHE (0.53) | ACHEDPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL17852152 | 0.95 | ACHE (0.54) | ACHEDPP7 | |
| SCHEMBL457464 | 0.93 | ACHE (0.57) | ACHEDPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL7534573 | 0.93 | ACHE (0.57) | ACHEDPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL7803301 | 0.90 | ACHE (0.62) | ACHEDPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL7797292 | 0.90 | ACHE (0.62) | ACHEDPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL7804961 | 0.90 | ACHE (0.62) | ACHEDPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL7804987 | 0.90 | ACHE (0.62) | ACHEDPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL19966782 | 0.88 | DPP7 (0.46) | ACHEDPP7GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133839-A1 | METHODS OF PREPARING N6-((2-AZIDOETHOXY)CARBONYL)LYSINE | Synthorx, Inc. (US) | 2021-07-01 | — | — | WO | disclosed |
| WO-2021093633-A1 | LONG-ACTING INTERLEUKIN-2 FOR TARGETING REGULATORY T CELLS AND USE THEREOF IN TREATMENT OF AUTOIMMUNE DISEASES | 中国医学科学院北京协和医院 | 2021-05-20 | — | — | WO | disclosed |