SCHEMBL22375753

SCHEMBL22375753

NCCOC(=O)NCCCCC(N)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.53
OTC P00480 1/20 0.44
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
ACHE P22303 7/20 0.42
DDAH1 O94760 1/20 0.42
DPP8 Q6V1X1 1/20 0.42
DPP7 Q9UHL4 1/20 0.42
ARG2 P78540 4/20 0.41
ARG1 P05089 3/20 0.41
ANPEP P15144 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24945952 1.00 GSR (0.53) GSROTCGNAI3GNAO1GNAI1
SCHEMBL18924694 1.00 GSR (0.53) GSROTCGNAI3GNAO1GNAI1
SCHEMBL20192790 0.95 GSR (0.50) GSROTCACHEDDAH1ARG2
SCHEMBL20192789 0.92 GSR (0.56) GSROTCGNAI3GNAO1GNAI1
SCHEMBL19246101 0.89 GSR (0.56) GSROTCGNAI3GNAO1GNAI1
SCHEMBL18924756 0.88 GSR (0.53) GSROTCACHEDDAH1ARG2
SCHEMBL19966765 0.87 GSR (0.52) GSROTCGNAI3GNAO1GNAI1
SCHEMBL23608137 0.86 ACHE (0.53) GNAI3GNAO1GNAI1ACHEDPP7
SCHEMBL23385458 0.86 ACHE (0.53) GNAI3GNAO1GNAI1ACHEDPP7
SCHEMBL23607693 0.86 ACHE (0.53) GNAI3GNAO1GNAI1ACHEDPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024040453-A1 MUTATED INFLUENZA VIRUS, PHARMACEUTICAL COMPOSITION, AND USE 北京大学宁波海洋药物研究院 2024-02-29 WO disclosed
US-20230183298-A1 CARRIER PROTEIN SUBJECTED TO SITE-DIRECTED MUTATION AND USE THEREOF IN PREPARATION OF VACCINE CANSINO BIOLOGICS INC. (CN) 2023-06-15 US disclosed
WO-2021133839-A1 METHODS OF PREPARING N6-((2-AZIDOETHOXY)CARBONYL)LYSINE Synthorx, Inc. (US) 2021-07-01 WO disclosed
US-20200268870-A1 MUTANT VIRUS, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF PEKING UNIVERSITY (CN) 2020-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200268870-A1 MUTANT VIRUS, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF UPF1, CPSF7, CPSF1 GSR 2114/4885OTC 1459/4885GNAI3 1038/4885
US-20230183298-A1 CARRIER PROTEIN SUBJECTED TO SITE-DIRECTED MUTATION AND USE THEREOF IN PREPARATION OF VACCINE PCTP, PLTP, ASGR1 GSR 829/4885OTC 1286/4885GNAI3 1671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.